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PUREfrex®
based on the PURE system
PUREfrex® kit is a reconstituted in vitro Coupled Transcription/Translation Systems, completely different from an E.coli extract S30 system.
By adding DNA or mRNA that encodes the target protein to the reaction solution, proteins can be synthesized easily and quickly without using living cells.
- Rebuilt cell-free system
- Tunable for your biologics
- Simple, Fast
- Suited for High Throuput Expression (for AI/ML)
- Very low contaminants
- Eco-Friendly Peptides synthesis
- Scalable from μL to L


About GeneFrontier Corporation
GeneFrontier Corporation is a biotechnology company based in Japan, dedicated to enabling cutting-edge research and development through advanced in vitro protein synthesis technologies.
As a subsidiary of Kaneka Corporation, a global leader in diversified chemical and biotech solutions, we leverage strong scientific expertise and industrial reliability.
Our flagship product, PUREfrex®, is a reconstituted cell-free protein synthesis system designed for high efficiency, flexibility, and scalability, which is suitable for protein engineering, synthetic biology, and drug discovery.
Products

Cell-free Protein Synthesis Kits
A product lineup of reconstituted cell-free protein synthesis kits developed based on the PURE system technology.

Supplements - Chaperones -
Optional kit for adding PUREfrex® to assist proper folding of protein.

Supplements - Forming disulfide bonds -
Optional kit for adding PUREfrex® to assist protein disulfide bond formation.

Other proteins
Optional kit for adding PUREfrex® to assist synthesis of proteins with rare sequences.

PUREfrex® Custom - Made to order –
This service allows you to freely customize the composition of each solution included in the PUREfrex® catalog products.